Estimates of the global space economic activity at approximately $415 billion offer a glimpse into the future of the industry beyond satellite communications and launch services. Decreasing cost to access low-Earth orbit (LEO) and increasing demand of space-enabled data for remote sensing and reliable low latency system requirements are driving global investment and production in the space sector. While today’s space sector offers a mature set of LEO-based market products, the next phase of growth for the space sector will be off-Earth economic activities to include commercial research and development, manufacturing, energy exploration and mining, and even agricultural outputs. This portion of the summit will concentrate on the global participants pushing into this new economic realm including commercial spaceport sites, new technologies driving manufacturing innovation, and public-private partnerships to set the course for deployment of new space-based systems.