| Sunday, September 12, 2021 |
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| CCC100 Opening Session | 5:00 PM - 6:00 PM | U.S. Chamber Headquarters - Lee Anderson | | |
| Reception & Dinner | 6:00 PM - 8:00 PM | U.S. Chamber Headquarters - Rooftop | | |
| Monday, September 13, 2021 |
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| CCC100 General Session | 10:00 AM - 11:30 AM | U.S. Chamber Headquarters - Lee Anderson | | |
| Working Lunch | 11:45 AM - 12:45 PM | U.S. Chamber Headquarters | | |
| CCC100 Live / LEAD Virtual General Session | 1:00 PM - 3:00 PM | U.S. Chamber Headquarters - Lee Anderson | | |
| Spy Museum Reception | 6:00 PM - 9:00 PM | Spy Museum | | |
| Tuesday, September 14, 2021 |
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| Exclusive CCC100 National Security Briefing | 9:00 AM - 11:30 AM | FBI Headquarters | | |
| LEAD Virtual Workshops | 11:00 AM - 4:00 PM | Sofitel - Paris Ballroom | | |
| CCC100 CEO Executive Strategy Session - Lunch | 11:45 AM - 1:00 PM | Sofitel - Paris Ballroom | | |
| CCC100 Closing Session | 5:00 PM - 6:00 PM | U.S. Chamber Headquarters - Lee Anderson | | |
| Washington Nationals vs. Miami Marlins Baseball Game | 7:05 PM | Nationals Park | | |